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For the micro: there's lots of evidence from Shapiro and McClintock, where cells actively engage in swapping genes to survive stressful environments. The point? Organisms are PROGRAMMED to adapt, adjust, morph, in a plastic way, to survive. But there are limits: in reproduction, sterility and weak strains result from hybridation across too wide a gap. (There's also hybrid vigor though which is sought out for mixing gene pools within a species.) So programmed survival changes vs. leaps and bounds imagination, or off limits jumps. You get the idea.
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